[Neglected case of uterine leiomyoma--case report].

Introduction: Uterine leimyomas are the most common gynaecologacal tumors and represent 30% of all benign gynecological tumors. The vast majority of leiomyomas are asymptomatic and do not need to be treated. Pelvic pain and abnormal uterine bleeding should be considered as the most important reasons for surgical treatment of uterine fibroids.

[Psychophysiologic disturbances in early postmenopause in women after physiological and surgical menopause].

Background/aim: The most common secondary manifestations of menopause are clinical manifestations of estrogen deficiency. They could be early and late. The aim of this study was to compare manifestations of somatic disturbances in early postmenopause in women after physiological and surgical menopause.

[The influence of aging on pathologic and immunobiologic parameters of invasive ductal breast carcinoma].

Background/aim: Most human cancers, including breast one, increase in frequency with aging. The aim of this study was to explore the hypothesis that aging also alters breast cancer biology.

Methods: The study included 120 women with primary invasive ductal carcinoma of the breast.

[Immunohistochemical analysis of angiogenesis in invasive ductal breast carcinoma with correlations to clinicopathological factor].

Background/aim: Angiogenesis is the formation of new vessels from preexisting ones. The aim of our study was to determine the relevance of tumor-induced angiogenesis, its correlation with some of the commonly used clinical, pathological factors and the recent biological indicators, and metastatic potential of the tumor in a series of 120 patients with invasive ductal carcinoma of the breast.

Methods: The identification of microvessels was performed immunohistochemically with factor VIII-related antigen.