Publications by authors named "Katarina Dostalova"
Real-world outcomes of mepolizumab treatment in severe eosinophilic asthma patients - retrospective cohort study in Slovakia.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
September 2023
Article Synopsis
- Mepolizumab, a monoclonal antibody targeting IL-5, is effective in improving asthma control and lung function in severe eosinophilic asthma patients based on real-world data from Slovakia.
- A retrospective study analyzed medical records of 17 adult asthma patients who started mepolizumab treatment between 2017 and 2019, focusing on changes in health over a year.
- Results showed significant reductions in severe exacerbations, blood eosinophil counts, and oral corticosteroid use, along with improved lung function and a decrease in nasal polyps, supporting mepolizumab's efficacy in routine clinical practice.
Introduction: Omalizumab was proven to be effective and safe in patients with moderate-to-severe allergic asthma. However, there is no direct evidence of the benefits of add-on omalizumab in real-life practice in the Slovakian population.
Aim: This subgroup analysis assessed the real-life effectiveness and safety of omalizumab in Slovakian patients with severe allergic asthma enrolled in the eXpeRience registry.