Publications by authors named "Katanuma A"
Article Synopsis
- Major hepatectomy (MH) can lead to a higher risk of adverse events due to reduced liver function and surgical impact, prompting an analysis within the JCOG1113 trial focused on gemcitabine-based treatments for advanced biliary tract cancer.* -
- Among 354 patients, 76 were evaluated post-surgery for recurrence; results indicated that while platelet counts fell more in patients who underwent MH, anemia and white blood cell count decreases were less frequent compared to those who did not have MH.* -
- Overall survival rates were similar between MH and non-MH patients receiving gemcitabine with both S-1 and cisplatin, suggesting that gemcitabine-based chemotherapy maintains its safety and efficacy
Article Synopsis
- *The Subcommittee defined five types of I-EUS procedures based on their purpose and method: EUS-guided sampling, EUS-guided through-the-needle examination, EUS-guided drainage/anastomosis, ESCR procedures, and EUS-guided delivery.
- *The proposed classifications aim to clarify I-EUS procedures and will be updated as new techniques and concepts arise in the field.*
Objectives: Unresectable ampullary cancer (AC) is a rare disease entity. The risk factors for recurrent biliary obstruction (RBO) following endoscopic biliary stenting (EBS) for unresectable AC remain unknown. In this study we aimed to evaluate the cumulative RBO rate and to identify risk factors for RBO following palliative EBS in patients with unresectable AC.
View Article and Find Full Text PDFGallbladder wall thickening is relatively common in clinical settings, and for appropriate diagnosis, the size, shape, internal structure, surface contour, and vascularity of the gallbladder wall must be evaluated. Morphological evaluation is the most important; however, some gallbladder lesions resemble gallbladder cancer in imaging studies, making differential diagnosis challenging. Vascular evaluation is indispensable for a precise diagnosis in these cases.
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- The TOKYO criteria, initially proposed for standardized reporting of endoscopic transpapillary biliary drainage outcomes, face limitations in newer techniques like endoscopic ultrasound and device-assisted endoscopy.
- A new committee is updating these criteria to better reflect current clinical practices in managing various biliary conditions, recognizing the need for comprehensive outcome evaluations beyond just stent patency.
- The revised TOKYO criteria 2024 aim to enhance the design and reporting of clinical studies by introducing a "stent-demanding time" concept for a more thorough assessment of endoscopic biliary drainage outcomes.
Article Synopsis
- Precut papillotomy can be challenging due to difficulty identifying biliary orifices; this study investigates the effectiveness of Texture and Color Enhancement Imaging (TXI) compared to traditional White Light Imaging (WLI) for this purpose.
- The study analyzed 20 patients who had undergone bile duct cannulation, assessing how well evaluators could identify biliary orifices using both TXI and WLI in randomized image presentations.
- Results indicated that TXI offered better accuracy (50.6% vs. 35.6%), higher visibility scores, and greater color differentiation from surrounding tissue compared to WLI, suggesting TXI is a valuable tool for improving biliary cannulation outcomes.
Image-enhanced endoscopy (IEE) has advanced gastrointestinal disease diagnosis and treatment. Traditional white-light imaging has limitations in detecting all gastrointestinal diseases, prompting the development of IEE. In this review, we explore the utility of IEE, including texture and color enhancement imaging and red dichromatic imaging, in pancreatobiliary (PB) diseases.
View Article and Find Full Text PDFBackground: Endoscopic papillectomy (EP) is less invasive than surgery but procedure-related adverse events (AEs) still frequently occur. This study compared the benefits of EP using a new optimal endoCUT setting on the VIO (Erbe) electrosurgical unit (VIO-EP) with those using the conventional electrosurgical unit setting (ICC-EP, Erbe).
Methods: This multicenter, retrospective, comparative cohort study included 57 patients who underwent VIO-EP and 91 who underwent ICC-EP.
Article Synopsis
- The study evaluated treatment strategies for nonfunctioning small pancreatic neuroendocrine neoplasms (NF-spNENs) in a large Japanese cohort, with a focus on surgically resected cases.
- A total of 606 NF-spNENs were analyzed, revealing that tumor grade and size significantly impacted outcomes, including lymph node metastasis and recurrence.
- Findings suggest that treatment plans should prioritize personalized approaches based on tumor grading and size rather than relying solely on size for decision-making.
Introduction: Patients with COVID-19 have dysbiosis of the intestinal microbiota with altered metabolites in the stool. However, it remains unclear whether the differences among SARS-CoV-2 variants lead to differences in intestinal microbiota and metabolites. Thus, we compared the microbiome and metabolome changes for each SARS-CoV-2 variant in patients with COVID-19.
View Article and Find Full Text PDFBackground: Aberrant DNA methylation is prevalent in colorectal serrated lesions. We previously reported that the CpG island of SMOC1 is frequently methylated in traditional serrated adenomas (TSAs) and colorectal cancers (CRCs) but is rarely methylated in sessile serrated lesions (SSLs). In the present study, we aimed to further characterize the expression of SMOC1 in early colorectal lesions.
View Article and Find Full Text PDFObjective: Few reports have explored the application of urinary trypsinogen-2 measurement in the early diagnosis of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis, and none have demonstrated the benefits of noninvasive testing. This study aimed to evaluate the clinical application of the rapid urinary trypsinogen-2 dipstick test (Nipro, Japan) compared with serum amylase and lipase levels for the early diagnosis of post-ERCP pancreatitis (PEP).
Methods: A total of 100 consecutive patients (54 men and 46 women) who were admitted and underwent ERCP at Tokyo Medical University Hospital from August 2021 to December 2021 were recruited.
Objective: We aimed to elucidate the feasibility of surveillance of patients with mucinous cystic neoplasm (MCN).
Methods: We performed a retrospective, multi-institutional study of 328 patients who underwent surgery for MCN at 18 Japanese institutions. Patients with MCN were divided into an immediate surgery group and a surveillance group, which underwent surgery after surveillance.
Objectives: We aimed to clarify the clinical utility of measuring serum pancreatic enzymes after endoscopic retrograde cholangiopancreatography (ERCP) for the purpose of predicting post-ERCP pancreatitis (PEP) by a meta-analysis of diagnostic test accuracy studies.
Methods: Studies on the prediction accuracy of PEP by serum amylase or lipase measured at 2, 3, and 4 h after ERCP were collected. A literature search was performed in PubMed and the Cochrane Library database for studies published between January 1980 and March 2023.
Tip-in endoscopic papillectomy for ampullary adenoma near diverticulum to minimize complications.
J Hepatobiliary Pancreat Sci
November 2023
Toyonaga and colleagues present a novel "tip-in endoscopic papillectomy" approach for resecting ampullary tumors, aiming to minimize complications like perforation and residual tumor by adapting the colonic polyp endoscopic mucosal resection tip-in method. The technique is described with accompanying video in a case of ampullary tumor near a diverticulum.
View Article and Find Full Text PDFBackground And Aims: We compared ERCP using a balloon-assisted endoscope (BE-ERCP) with EUS-guided antegrade treatment (EUS-AG) for removal of common bile duct (CBD) stones in patients with Roux-en-Y (R-Y) gastrectomy.
Methods: Consecutive patients who had previous R-Y gastrectomy undergoing BE-ERCP or EUS-AG for CBD stones in 16 centers were retrospectively analyzed.
Results: BE-ERCP and EUS-AG were performed in 588 and 59 patients, respectively.