Publications by authors named "Kata Husi"

Autologous stem cell transplantation (ASCT) is the standard treatment of primary refractory or relapsed Hodgkin-lymphoma, which can provide a cure rate of about 50%. The aim of our study was to analyze the data of 126 HL patients undergoing AHSCT in Hungary between 01/01/2016 and 31/12/2020. We assessed the progression-free and overall survival, the prognostic role of PET/CT performed before transplantation and effect of brentuximab vedotin (BV) treatment on survival outcomes.

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Objective: Although the majority of patients with Hodgkin lymphoma (HL) has recently become long-term survivors, 20%-30% of HL patients have primary refractory disease or relapse. It is essential to identify patients at risk of treatment failure during first-line therapy. To objective of the present study was to investigate the combined prognostic role of fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) imaging and thymus and activation-regulated chemokine (TARC) levels in Hodgkin lymphoma.

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Article Synopsis
  • * For patients who have been heavily treated and are not eligible for standard therapies, new options like Brentuximab-vedotin and combination regimens with drugs like rituximab and bendamustine show promise.
  • * The study suggests that a combination of rituximab and bendamustine, potentially with Brentuximab-vedotin, could serve as a viable alternative treatment for those patients who have gone through multiple therapies.
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