Aerobic performance in rats subjected to incremental-speed running exercise: A multiple regression analysis study emphasizing thermoregulation-related variables.

Single-variable analyses have limited ability to explain complex phenomena such as the regulation of prolonged physical (aerobic) performance. Our study aimed to identify predictors of performance in rats subjected to incremental-speed running exercise. Notably, most variables assessed were associated with rats' thermoregulation.

Determinants of body core temperatures at fatigue in rats subjected to incremental-speed exercise: The prominent roles of ambient temperature, distance traveled, initial core temperature, and measurement site.

Understanding the factors that underlie the physical exercise-induced increase in body core temperature (T) is essential to developing strategies to counteract hyperthermic fatigue and reduce the risk of exertional heatstroke. This study analyzed the contribution of six factors to T attained at fatigue in Wistar rats (n = 218) subjected to incremental-speed treadmill running: ambient temperature (T), distance traveled, initial T, body mass, measurement site, and heat loss index (HLI). First, we ran hierarchical multiple linear regression analyses with data from different studies conducted in our laboratory (n = 353 recordings).