Evaluating effect of salt leaching method on release and swelling rate of metformin nanoparticles loaded-chitosan/polyvinyl alcohol porous composite.

In this study, salt leaching (SL) technique was used to prepare a chitosan/polyvinyl alcohol (CS/PVA) polymeric composite in order to load metformin nanoparticles (METNPs). Sodium chloride was added to the CS/PVA (0.5:0.

Development and evaluation of sodium alginate-basil seeds mucilage beads as a suitable carrier for controlled release of metformin.

Sodium alginate (SA) is a natural biopolymer that is used as biodegradable and non-toxic material in medical and pharmaceutical fields. Although crosslinked SA with calcium ions in the presence of monovalent salts are unstable. The aim of this work is to employe plant mucilage in combination of SA beads to improve the properties of SA beads.