Green algae compounds as antiviral candidates for SARS-CoV-2: In silico study.

Green algae () are known to contain bioactive compounds which are hypothesized to have antiviral activities against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19) pandemic. The aim of this study was to analyze the anti-SARS-CoV-2 potential of compounds extracted from the green alga using in silico analysis. The extract was obtained through maceration with 96% ethanol and the compounds present in the extract were identified through gas chromatography-mass spectroscopy (GC-MS).

New Crambescidin-Type Alkaloids from the Indonesian Marine Sponge Clathria bulbotoxa.

A crude methanolic extract of the Indonesian sponge showed a potent cytotoxic activity against the human epidermoid carcinoma A431 cells. An investigation of the active components led to the isolation of three new compounds named crambescidins 345 (), 361 (), and 373 (), together with the known related metabolites crambescidins 359 (), 657 (), and 800 (). The structures of the compounds were determined by spectroscopic analysis.