Conventional Versus Inverted Side-cut Flaps for Femtosecond Laser-Assisted LASIK: Laboratory and Clinical Evaluation.

Purpose: To study the differences in early corneal cellular events and biomechanical properties after femtosecond laser-assisted LASIK performed using conventional or inverted side-cut angles.

Methods: In the laboratory study, left eyes of 24 rabbits underwent LASIK flap creation with a 70° or 115° side-cut. The contralateral eyes served as controls.

Assessing sodium iodate-induced outer retinal changes in rats using confocal scanning laser ophthalmoscopy and optical coherence tomography.

Purpose: Sodium iodate induces RPE atrophy and photoreceptor degeneration, as seen in the pathogenesis of many retinal diseases. We investigated a new approach of analyzing retinal images using confocal scanning laser ophthalmoscopy (cSLO) that allows longitudinal assessment of sodium iodate-induced lesions in the retina of living rats.

Methods: A single dose of sodium iodate (25-75 mg/kg) was given intravenously to adult Sprague-Dawley rats.

Isoliquiritigenin from licorice root suppressed neovascularisation in experimental ocular angiogenesis models.

Aim: To explore the antiangiogenic property of isoliquiritigenin (ISL) on in vivo and in vitro models.

Design: Laboratory investigation.

Methods: The effect of ISL on angiogenesis development was investigated using ex ovo chick chorioallantoic membrane model.