Publications by authors named "Kashamalla Chinna Ashalu"
Herein, we demonstrate the first total synthesis of Macrotricolorin A and its enantiomer from the key intermediate which is accessible from two precursors phenol and resorcinol, by two different sequences. Macrotricolorin A possesses anti-inflammatory properties and is a novel diarylpropanoid. The first total synthesis of Macrotricolorin A was accomplished using simple reactions such as Williamson's etherification, Claisen-Schmidt condensation, reduction, and chiral resolution.
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- The use of iron in catalysis is gaining attention due to its abundance, biocompatibility, and low cost, making it a strong alternative to expensive noble metals.
- Direct C-H functionalization is a key method for adding new functional groups to organic molecules, which is crucial given the prevalence of C(sp )-H bonds in many compounds.
- The review discusses the effectiveness, selectivity, and challenges of using iron catalysts in C(sp )-H activation, providing a summary of advancements up to 2022.