PREPARE: A Stepped-Wedge Cluster-Randomized Trial to Evaluate Whether Risk Stratification Can Reduce Preterm Deliveries Among Patients With Suspected or Confirmed Preterm Preeclampsia.

Background: Early delivery in preterm preeclampsia may reduce the risks for the patient, but consequences of prematurity may be substantial for the baby. This trial evaluated whether the implementation of a risk stratification model could safely reduce prematurity.

Methods: This was a stepped-wedge cluster-randomized trial in seven clusters.

The Global Pregnancy Collaboration (CoLab) Biobank of rare placentas.

Many adverse pregnancy outcomes are the result of placental disorders. It has been difficult to decipher the root cause of many of these disorders due to an overlap in identifiable placental pathology and pregnancy outcomes. The reason for this confusion may be related to the lack of an appropriate control placenta.