Synthesis and characterizations of natural limestone-derived nano-hydroxyapatite (HAp): a comparison study of different metals doped HAps on antibacterial activity.

Earth-abundant mineral limestone obtained from North Sumatera, Indonesia, has been utilized to synthesize nano-hydroxyapatite (HAp). Although HAp is biocompatible to the human bone, its antibacterial activity is still very low. Herein, different metal ions (, Ag, Cu, Zn, and Mg) were doped into HAp to improve the antibacterial activity.

Investigation of Antibacterial Activity and Cell Viability of Ag/Mg and Ag/Zn Co-doped Hydroxyapatite Derived from Natural Limestone.

Improving the antibacterial activity to avoid infections and keeping the biocompatibility at a safe level of HAp-based materials is highly important for biomedical applications. In this work, we investigate the antibacterial activity of 2.5Ag/2.