Publications by authors named "Karunakar R Pothula"
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Synopsis of recent research by authors named "Karunakar R Pothula"
- Karunakar R Pothula's research primarily focuses on the structural biology of viral proteins, particularly HIV-1 envelope glycoproteins and Langya virus fusion proteins, exploring their conformational states to understand interactions with broadly neutralizing antibodies and immune responses!
- Recent studies highlight the significance of conformational flexibility in HIV-1 Envs, which can impact the design of immunogens for HIV vaccines, as well as advancements in modeling ligands bound to proteins using cryo-electron microscopy (cryo-EM) techniques to enhance reproducibility and accuracy in structural determinations!
- Pothula's contributions also include significant findings related to amyloid fibrils associated with diseases like type 2 diabetes and the mechanism of antimicrobial peptides, revealing important insights into the structural dynamics of proteins in health and disease!
