Publications by authors named "Karthikeyan Kumaraswamy"
Is a differentiated care model needed for patients with TB? A cohort analysis of risk factors contributing to unfavourable outcomes among TB patients in two states in South India.
Reynold Washington Rajaram Subramanian Potty A Rajesham T Seenappa Anil Singarajipura Karthikeyan Kumaraswamy
BMC Public Health
July 2020
Article Synopsis
- The study aims to identify risk factors that lead to unfavorable treatment outcomes for tuberculosis (TB) patients in India, in order to create a better care model for at-risk individuals.
- Conducted as part of a USAID-THALI project in Karnataka and Telangana, the research involved Community Health Workers assessing TB patients for potential risks and following their treatment outcomes.
- Results showed that patients with one or more risk factors—such as being male, having low education, being underweight, having HIV, and previous treatment history—were significantly more likely to experience death or unfavorable outcomes compared to those with no risks.
Background: Emergence of carbapenem resistance among in different geographical regions is of great concern as these bacteria are easily transmissible among patients. Carbapenem-resistance in is due to production of carbapenemases of various classes and hyper production of the ESBLs (Extended spectrum beta lactamases) and Amp C beta lactamases with reduced cell wall permeability mechanisms. Phenotypic detection and differentiation is important for proper infection control and appropriate patient management.
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