Publications by authors named "Karthikeyan Kaliaperumal"

Article Synopsis
  • Diseases classified under non-LCH often have similar clinical and histological characteristics, making diagnosis difficult.
  • A two-year-old girl exhibited various asymptomatic skin lesions, leading to a provisional diagnosis of generalized eruptive histiocytosis (GEH), which was later found to have overlapping features with juvenile xanthogranuloma (JXG).
  • The case highlights the importance of careful differentiation between GEH and JXG since they may require different treatment approaches, demonstrating that clinical observation alone can be misleading due to their similarities.
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Chikungunya fever (CKF), a neglected tropical disease caused by the chikungunya virus, manifests with skin pigmentary changes in a significant portion of people. A myriad of pigmentary alterations in individuals with CKF have been documented in the literature. This review highlights the pathogenesis, clinical features, histopathology, diagnosis and treatment of CKF-associated pigmentation.

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Aluminium, the third most abundant element in the earth's crust, was long considered virtually innocuous to humans but has gained importance in the recent past. Aluminium is ubiquitous in the environment, with various sources of exposure like cosmetics, the food industry, occupational industries, the medical field, transport and electronics. Aluminium finds its utility in various aspects of dermatology as an effective haemostatic agent, anti-perspirant and astringent.

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Background: Dermatosis neglecta (DN) is an acquired skin condition that occurs due to unconscious neglect of self-cleaning in individuals with some underlying risk factor.

Aims And Objectives: The purpose of this study was to summarize the demographic, clinical characteristics, and treatment outcomes of patients with DN in a tertiary care center.

Methods: We evaluated the medical records of 28 patients with DN who were diagnosed and treated in our center between August 2020 and July 2022.

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Interleukin-36 (IL-36) cytokines contribute to the pathogenesis of various inflammatory skin conditions and are potential therapeutic targets. Spesolimab is a monoclonal antibody that inhibits IL-36 signaling recently approved by the Food and Drug Administration for the management of generalized pustular psoriasis flares in adults. Clinical trials are evaluating the efficacy of this monoclonal antibody in a few other dermatological conditions.

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Reticulate pigmentary dyschromatoses primarily include dyschromatosis universalis hereditaria (DUH), dyschromatosis symmetrica hereditaria (DSH) (Reticulate acropigmentation of Dohi), and unilateral dermatomal pigmentary dermatosis, which differ in their patterns of distribution. The disease was initially described by Ichikawa and Hiraga in Germany in 1933. The prevalence of DUH is 0.

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Article Synopsis
  • - Hair dyeing, which dates back to ancient Egypt, has evolved from being used mainly to cover grey hair in the elderly to a popular fashion choice among younger people.
  • - The main concern surrounding hair dye use is contact dermatitis, particularly due to para-phenylenediamine (PPD), an allergen that can cause allergic reactions in a small percentage of the population.
  • - The article discusses the adverse effects of hair dye, including skin issues and potential health risks, while advocating for safer alternatives and emphasizing the importance of testing and preventative measures.
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Turmeric is the dried rhizome of Linn which is extensively used in Indian culture. Curcumin is its most active pharmaceutical component. Turmeric use is very closely related with the socio-religious life of the population.

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