Publications by authors named "Karthikeyan A"

The studies conducted in this contribution are based on the analysis of the dynamics of a homogeneous network of five inertial neurons of the Hopfield type to which a unidirectional ring coupling topology is applied. The coupling is achieved by perturbing the next neuron's amplitude with a signal proportional to the previous one. The system consists of ten coupled ODEs, and the investigations carried out have allowed us to highlight several unusual and rarely related dynamics, hence the importance of emphasizing them.

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To illustrate the occurrences of extreme events in the neural system we consider a pair of Chialvo neuron maps. Importantly, we explore the dynamics of the proposed system by including a flux term between the neurons. Primarily, the dynamical behaviors of the coupled Chialvo neurons are examined using the Lyapunov spectrum and bifurcation analysis.

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Article Synopsis
  • The integration of genomic medicine into the NHS can enhance disease prediction and personalized treatment but faces several challenges, such as unclear eligibility criteria and access disparities.
  • Key proposed solutions include extending genetic test authority to general clinicians, improving workforce training, and standardizing guidelines for genomic testing across the UK.
  • Utilizing AI and better data management systems can help streamline the process, ultimately improving patient outcomes and advancing precision medicine in healthcare.
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Rice bean is an underutilized legume crop cultivated in Asia, and it is a good source of protein, minerals, and essential fatty acids for human consumption. Moreover, the leaves left over after harvesting rice bean seeds contain various biological constituents beneficial to humans and animals. In our study, we performed a de-novo transcriptome assembly of rice bean, characterized the WRKY transcription factors, and studied their response to aluminum stress.

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Background: Physician grief, as defined by Kenneth Doka as disenfranchised grief, refers to "the grief that individuals experience when they incur a loss that is not openly acknowledged, publicly mourned, or socially supported." The experience of patient deaths on the emotional health of young doctors is unknown. The after-effects like stress, anxiety, burnout, depression, and others indirectly have a potential impact on decision-making and patient care.

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In this study, the hybrid conductance-based adaptive exponential integrate and fire (CadEx) neuron model is proposed to determine the effect of magnetic flux on conductance-based neurons. To begin with, bifurcation analysis is carried out in relation to the input current, resetting parameter, and adaptation time constant in order to comprehend dynamical transitions. We exemplify that the existence of period-1, period-2, and period-4 cycles depends on the magnitude of input current via period doubling and period halving bifurcations.

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Green nanotechnology is the emerging field of research in recent decades with growing interest rapidly. This integrates green chemistry with green engineering to avoid using toxic chemicals in the synthesis of organic nanomaterials. Green nanotechnology would create a huge potential for the use of nanoparticles for more sustainable utilization in improving animal health.

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Background: Bioinspired nanomaterials have widely been employed as suitable alternatives for controlling biofilm and pathogens due to their distinctive physico-chemical properties.

Methodology: This study explored the antibiofilm as well as photocatalytic potential of silver (Ag) nanoparticles (NPs) synthesized using the cell-free supernatant of Lactobacillus acidophilus for the disinfection of multi-drug-resistant (MDR) strains of enteroaggregative E. coli (EAEC), Salmonella Typhimurium, S.

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Background: Prognostic nutritional index (PNI) and systemic immune-inflammatory index (SII) are two novel markers that have emerged as potential candidates as an early indication of the severity of the disease in coronavirus disease 2019 (COVID-19) patients.

Objective: The objective of the study is to assess the utility of the prognostic nutritional index (PNI) and systemic immune-inflammatory index (SII) as markers of severity among patients with COVID-19 infection.

Methods: This is a retrospective study conducted in a tertiary care centre in South India.

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Marine microorganisms offer a promising avenue for the eco-friendly synthesis of nanoparticles due to their unique biochemical capabilities and adaptability to various environments. This study focuses on exploring the potential of a marine bacterial species, Stenotrophomonas rhizophila BGNAK1, for the synthesis of biocompatible copper nanoparticles and their application for hindering biofilms formed by monomicrobial species. The study begins with the isolation of the novel marine S.

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Attention-deficit/hyperactivity disorder (ADHD) has been one of the leading causes of neuropsychiatric disorders among children, which is why it is extremely essential to have a clear understanding of the disease and the new and upcoming treatment options available. Yoga has been one of the most recently explored and newer techniques that have been employed in the treatment of this disorder. It has become extremely crucial to understand the importance of using supportive treatments in the management of ADHD owing to the innumerable side effects caused by stimulant medication and the growing demands of parental concern about starting their children on stimulant medication at a very young age.

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Micro/nanoplastics are widespread in terrestrial ecosystem. Even though many studies have been reported on the effects of these in marine environment, studies concerning their accumulation and impact on terrestrial ecosystem have been scanty. The current study was designed to determine how terrestrial plants, especially legumes, interact with micro/nanoplastics to gain insights into their uptake and translocation.

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A genetic linkage map representing the pearl millet genome was constructed with SNP markers. Major and stable QTL associated with flowering, number of productive tillers, ear head length, and test weight were mapped on chromosomes 1 and 3. Pearl millet (Pennisetum glaucum) is a major cereal and fodder crop in arid and semi-arid regions of Asia and Africa.

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Background and objective Acute myeloid leukemia (AML) is a heterogeneous and aggressive blood malignancy prevalent among both children and adults, accounting for a significant proportion of acute leukemia cases worldwide. Our study aimed to shed light on the demographic and clinical profile and risk stratification of newly diagnosed AML cases at a tertiary care government hospital in South India. Methods We conducted a cross-sectional study involving 221 patients with AML in the Department of Clinical Hematology, Rajiv Gandhi Government General Hospital and Madras Medical College, Chennai, Tamil Nadu from January 2020 to December 2022.

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This study explores the inherent nonlinearity of quarter car models by employing an experimental and numerical approach. The dynamics of vehicular suspension systems are pivotal for ensuring passenger comfort, vehicle stability, and overall ride quality. In this paper we assessed the impact of various parameters and components on suspension performance, enabled the optimization of ride comfort, stability, and handling characteristics.

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Purpose Of Review: The world is proliferating rapidly, with science and technology advancing at an incredible rate. These advances have, however, ushered in an age with a rise in social isolation (SI) and loneliness. SI is an objective term that refers to lacking social contact or support.

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Objective: Sympathetic innervation plays a pivotal role in regulating cardiovascular health, and its dysregulation is implicated in a wide spectrum of cardiovascular diseases. This study seeks to evaluate the impact of denervation of the abdominal aorta on its morphology and wall homeostasis.

Methods: Male and female Sprague-Dawley rats (N = 12), aged 3 months, underwent midline laparotomy for infrarenal aorta exposure.

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Skin, the largest organ in the body, blocks the entry of environmental pollutants into the system. Any injury to this organ allows infections and other harmful substances into the body. 3D bioprinting, a state-of-the-art technique, is suitable for fabricating cell culture scaffolds to heal chronic wounds rapidly.

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Background: This research delves into the reproductive toxicology of zinc oxide nanoparticles (ZnO-NPs) in male Sprague Dawley rats. It specifically examines the repercussions of Zn accumulation in the testes, alterations in testosterone levels, and histopathological changes in the gonadal tissues.

Aims: The primary objective of this study is to elucidate the extent of reproductive toxicity induced by ZnO-NPs in male Sprague Dawley rats.

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Introduction: Time in range (TIR), a metric of continuous glucose monitoring (CGM) provides better information regarding the individual's glycemic variability than a static measure like glycated hemoglobin (HbA1c). TIR is emerging as an independent risk factor for diabetic complications, both microvascular and macrovascular complications independent of HbA1c. Hence, this study evaluates the association between TIR and cardiac autonomic neuropathy (CAN) in type 2 diabetic patients.

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(PA), a Gram-negative pathogen, is a common cause of nosocomial infections, especially in immunocompromised and cystic fibrosis patients. PA is intrinsically resistant to many currently prescribed antibiotics due to its tightly packed, anionic lipopolysaccharide outer membrane, efflux pumps, and ability to form biofilms. PA can acquire additional resistance through mutation and horizontal gene transfer.

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Introduction: COVID pandemic shifted healthcare-related education to digital platforms. With the widespread availability of learning management systems like MOODLE, many opportunities exist to create innovative e-modules. Its success depends on the interactive multimedia resources and structural framework.

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Studies in the literature have demonstrated the significance of the synchronization of neuronal electrical activity for signal transmission and information encoding. In light of this importance, we investigate the synchronization of the Chay neuron model using both theoretical analysis and numerical simulations. The Chay model is chosen for its comprehensive understanding of neuronal behavior and computational efficiency.

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