Publications by authors named "Karthik Vedantam"
Article Synopsis
- Patients with aortic stenosis (AS) often have calcified coronary artery disease, needing atherectomy to improve outcomes during percutaneous coronary intervention (PCI); however, there is limited data on the effectiveness of PCI with or without atherectomy for these patients.
- A study analyzed hospital data from 2016 to 2019, finding that 88.6% of AS patients underwent PCI-only, while 2.3% and 9.1% had orbital and non-orbital atherectomy respectively, with costs of atherectomy being higher than PCI-only.
- The results showed an increase in PCI procedures and the use of intravascular ultrasound (IVUS), indicating that IVUS-guided atherectomy
Article Synopsis
- This systematic review and meta-analysis focuses on the safety and effectiveness of dual antiplatelet therapy (DAPT) in elderly patients suffering from acute coronary syndrome (ACS).
- The study analyzed 8 clinical trials involving 29,217 patients, revealing that DAPT using prasugrel or ticagrelor carries a higher risk of bleeding events compared to clopidogrel, with a risk ratio of 1.17.
- However, there was no significant difference in treatment efficacy between these drugs and clopidogrel, indicated by a risk ratio of 0.85, suggesting that while bleeding risk is higher, the effectiveness remains similar.
Background: Patients with severe tricuspid regurgitation carry an elevated surgical risk resulting in increasing adoption of less invasive transcatheter therapies such as transcatheter tricuspid valve repair (TTVR); however, data are limited. This study aimed to describe patient characteristics and predictors of poor outcomes among those undergoing TTVR.
Methods: The National Inpatient Sample was queried (2016-2019) to identify all patients undergoing TTVR ( code 02UJ3JZ) alone or in combination with mitral transcatheter edge-to-edge repair (MTEER) (code 02UG3JZ).
Background: Although many patients with coronavirus disease 2019 (Covid-19) require direct admission to the intensive care unit (ICU), some are sent after admission. Clinicians require an understanding of this phenomenon and various risk stratification approaches for recognizing these subjects.
Methods: We examined all Covid-19 patients sent initially to a ward who subsequently required care in the ICU.
Introduction: The pandemic of the coronavirus disease 2019 (COVID-19) and associated pneumonia represent a clinical and scientific challenge. The role of Extracorporeal Membrane Oxygenation (ECMO) in such a crisis remains unclear.
Methods: We examined COVID-19 patients who were supported for acute respiratory failure by both conventional mechanical ventilation (MV) and ECMO at a tertiary care institution in Washington DC.
Cardiovascular disease (CVD), especially ischemic heart disease and stroke, is the major cause of death worldwide, accounting for more than one-third of all deaths annually. Hypertension is the most prevalent and modifiable risk factor of CVD-related deaths. The same is true for obesity, which is currently being recognized as a major global epidemic.
View Article and Find Full Text PDF