Publications by authors named "Karthik Marimuthu Muthukumar"
Article Synopsis
- - The study explores how genetic, lifestyle, and gut microbiome factors contribute to differences in mental health improvements during weight-loss interventions for individuals with neuropsychiatric diseases and obesity.
- - Participants in the study, who were part of a digital health program, lost an average of 5.4% of their body weight, and over 95% reported improved mental health symptoms, indicating a potential link between weight loss and mental well-being.
- - Significant correlations were found between genetic scores and mental health conditions like anxiety and depression, as well as between gut microbial functions and sleep problems, suggesting that both genetics and gut health play roles in how individuals respond to weight-loss interventions in terms of mental health.
Background: The COVID-19 pandemic has highlighted the urgency of addressing an epidemic of obesity and associated inflammatory illnesses. Previous studies have demonstrated that interactions between single-nucleotide polymorphisms (SNPs) and lifestyle interventions such as food and exercise may vary metabolic outcomes, contributing to obesity. However, there is a paucity of research relating outcomes from digital therapeutics to the inclusion of genetic data in care interventions.
View Article and Find Full Text PDF