Publications by authors named "Karthik H"

Article Synopsis
  • * Over four years, partnerships were formed with local health providers in 13 remote communities to create a sustainable eye care model, which included screening 378 patients and identifying several cases of diabetic eye diseases.
  • * The initiative improved access to eye care, streamlined specialist referrals, and built healthcare workers' skills, proving that regular eye exams can effectively catch eye diseases early in remote populations.
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The liver has excellent regeneration potential and attains complete functional recovery from partial hepatectomy. The regenerative mechanisms malfunction in chronic liver diseases (CLDs), which fuels disease progression. CLDs account for 2 million deaths per year worldwide.

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Article Synopsis
  • Fungal keratitis is a serious eye condition in tropical Australia that can lead to blindness, prompting a study of its clinical and microbiological characteristics from 2014-2022 at Royal Darwin Hospital.
  • The study involved 31 patients, revealing that Aboriginal and Torres Strait Islander individuals were significantly younger at diagnosis and presented later for treatment compared to non-Indigenous patients; common risk factors included contact lens use and eye injuries.
  • A diverse range of fungal species were identified, highlighting the need for improved access to eye health services in rural areas, especially for Indigenous populations, to reduce high rates of morbidity.
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Mucormycosis is a rare, but potentially fatal, fungal infection which is caused by mucormyctes. These forms of fungi are typically known to infect immuno-compromised individuals but are rare in immunocompetent individuals. Herein, we report the case of a 52 year-old female who was diagnosed with right breast carcinoma in Manipal Hospital, a tertiary cancer care center.

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Oxalate toxicity is mediated through generation of reactive oxygen species (ROS) via a process that is partly dependent on mitochondrial dysfunction. Here, we investigated whether C-phycocyanin (CP) could protect against oxidative stress-mediated intracellular damage triggered by oxalate in MDCK cells. DCFDA, a fluorescence-based probe and hexanoyl-lysine adduct (HEL), an oxidative stress marker were used to investigate the effect of CP on oxalate-induced ROS production and membrane lipid peroxidation (LPO).

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Background: Oral submucous fibrosis is a chronic, insidious oral mucosal condition affecting the most parts of the oral cavity with high malignant transformation rate triggered by areca nut chewing, nutritional deficiencies, immunologic processes, and genetic predisposition. OSF causes significant hematological abnormalities resulting in anemia and a decrease in serum iron levels.

Aim: The aim of this study was to estimate the hemoglobin and serum iron levels among patients with oral submucous fibrosis and to compare the values with healthy subjects.

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