In this present study, microwave pre-treatment has been used for sustainable biofuel production from three different biowastes through catalytic aided co-pyrolysis techniques. The experimental investigations have been carried out to develop biofuel at temperature (350-550℃), heating rate (15-50℃/min) and particle size (0.12-0.
View Article and Find Full Text PDFAlcohols could be the biggest factor for the improvement of world biofuel economy in the present century due to their excellent properties compared to petroleum products. The primary concerns of sustainable alcohol production for meeting the growing energy demand owing to the selection of viable feedstock and this might enhance the opportunities for developing numerous advanced techniques. In this review, the valorization of alcohol production from several production routes has been exposed by covering the traditional routes to the present state of the art technologies.
View Article and Find Full Text PDFAn increase in population, rapid urbanization and industrialization has accelerated the rate of municipal solid waste generation. The current disposal of solid waste is a burgeoning issue and it's in immediate need to shift the existing disposal processes to a sustainable manner. Circular economy (CE) is a conceptual model which is been used for better use of resources and minimization of waste in a closed loop approach which could be appropriate for waste management.
View Article and Find Full Text PDFObjective: Addiction is a growing public health problem which affects the person, the whole family, and society. The primary care physician (PCP) is often the first point of contact in the health care and can play a significant role in the early detection and intervention. It is well established that early intervention is associated with better outcomes.
View Article and Find Full Text PDFObjective: Alzheimer's disease (AD) is characterized with an abnormal deposition of insoluble amyloid-beta (Aβ) peptide plaques, tangles formation and synaptic dysfunction. These result in impaired functioning of neuronal circuits and alter the behavioral response owing to activation of neurotransmitter receptors. Recently, it has been implicated that Aβ influences N-methyl d-aspartate (NMDA) receptor activation in AD; however, the molecular mechanism underlying remains unclear.
View Article and Find Full Text PDFJ Alzheimers Dis
April 2018
Epidemiological studies state that dementia has multiple etiologies including genetic mutation, genetic variation, and environmental factors. Accumulating evidence suggests that dysregulation of cholesterol homeostasis is the major etiological factor in initiating neurodegeneration. Apolipoprotein E (APOE) polymorphic alleles and associated polymorphism of lipoprotein lipase (LPL) and cholesteryl ester transfer protein (CETP) that are important components in regulating cholesterol metabolism are implicated in neurodegenerative diseases.
View Article and Find Full Text PDFAlthough several drugs revealed moderate amelioration of symptoms, none of them have sufficient potency to prevent or reverse the progression toward Alzheimer's disease (AD) pathology. Resveratrol (RSV), a polyphenolic compound has shown an outstanding therapeutic effect on a broad spectrum of diseases like age-associated neurodegeneration, inflammation etc. The present study was thus conducted to assess the therapeutic efficacy of RSV in ameliorating the deleterious effects of Ibotenic acid (IBO) in male Wistar rats.
View Article and Find Full Text PDFTargeting BACE1 (β-site APP cleaving enzyme 1 or β-secretase) is the focus of Alzheimer's disease (AD) research because this aspartyl protease is involved in the abnormal production of β amyloid plaques (Aβ), the hallmark of its pathophysiology. Evidence suggests that there is a strong connection between AD and BACE1. As such, strategies to inhibit Aβ formation in the brain should prove beneficial for AD treatment.
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