Impact of the Insoluble Gas Concentration on Measured Stroke Volume at Rest and Submaximal Exercise Using the Innocor Device.

Introduction: The Innocor® device uses an insoluble gas (SF 6 ) to estimate lung volume and the rate of disappearance of a soluble gas (nitrous oxide) to measure pulmonary blood flow (PBF), which approximates cardiac output assuming no shunt. We sought to identify error in the measurement of the insoluble gas in an effort to reduce variation in Innocor® measurement.

Methods: We enrolled 28 participants from the Dallas Heart Study (mean age, 63 yr; 57% men; 43% White).