Publications by authors named "Karr Stinson"
Cancer Cell Int
April 2023
Article Synopsis
- The alpha-fetoprotein receptor (AFPR) is a promising target for cancer treatment since it's found on most cancers but not on normal tissues.
- Researchers tested a drug called ACT-101, combined with maytansinoid toxins, in mice with colorectal cancer, finding significant reductions in tumor size for several variations of the drug.
- One specific version, ACT-903, showed remarkable anti-tumor effects, with 90% of treated mice showing no detectable tumors and surviving past Day 60, suggesting strong potential for clinical use without major toxicity.
