Publications by authors named "Karpagam Subramanian"

Latent fingerprint imaging is a crucial tool for national security and crime recognition, requiring environmentally sustainable, nontoxic materials. To address this need, we have developed a green fluorescence-emitting material, THCHO, that binds effectively to latent fingerprints, enabling clear, high-resolution visualization. The solution produces strong green fluorescence that highlights fingerprint imprints with exceptional detail and contrast.

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Article Synopsis
  • The design and structure of hole-transporting materials (HTMs) are key to improving the efficiency of eco-friendly perovskite solar cells (PSCs) by preventing issues like corrosion and charge recombination.
  • Current HTMs have limitations such as high production costs and low stability, highlighting the need for affordable alternatives, particularly those derived from thiophene, which can enhance performance by interacting with surface defects in the perovskite layer.
  • Thiophene-based HTMs offer benefits like better passivation, increased environmental stability, and effective charge transfer, making them a promising solution for developing more durable and efficient solar cells.
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In this study, we designed and synthesized a novel compound (PTH-AB-PY) based on phenothiazine and pyridine moieties with aggregation-induced emission enhancement (AIEE) properties. The compound has shown exceptional selectivity and sensitivity towards ClO ions with an impressive detection limit of 6.86 × 10 M.

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A vibrant blue organic luminescent material with enhanced photophysical properties is in great demand for the generation of optoelectronic devices and luminescent sensors. In this context, the thiophene-benzimidazole probe TH-IMI was designed and synthesized by a simple condensation reaction. The synthesized probe has shown excellent photophysical properties like high FL intensity, a high quantum yield of 90% in the solution phase, a low optical bandgap of 2.

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A thirst for the development of a simple fluorescence probe for enhanced sensing application has been achieved by synthesizing a stupendous thiophene-appended benzothiazole-conjugated compound . The synthesized compound was characterized using nuclear magnetic resonance and mass spectrometry techniques. Furthermore, a photophysical property of and reveals the enhanced emission spectrum of because of a restricted spin-orbital coupling as a result of increased conjugation compared to the ligand .

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Heavy metal ions are extremely poisonous and cause long-term harm to living organisms. Among these ions, mercury is the most toxic metal and has no notorious purpose in the human body. In this regard, an elegant azomethine thiazole compound was synthesized, and it was found to be highly sensitive to three-way detection of mercury ions with detection limits of 0.

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Sustainable solutions on fabricating and using a face mask to block the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread during this coronavirus pandemic of 2019 (COVID-19) are required as society is directed by the World Health Organization (WHO) toward wearing it, resulting in an increasingly huge demand with over 4 000 000 000 masks used per day globally. Herein, various new mask technologies and advanced materials are reviewed to deal with critical shortages, cross-infection, and secondary transmission risk of masks. A number of countries have used cloth masks and 3D-printed masks as substitutes, whose filtration efficiencies can be improved by using nanofibers or mixing other polymers into them.

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Alzheimer's Disease (AD) is usually caused by intellectual deterioration which occurs due to the degeneration of cholinergic neurons. Donepezil is employed for cholinesterase enzyme Inhibition (ChEI) to treat AD in a wider population. Over the years, researchers finding difficulties prompted through traditional dosage forms particularly in geriatric patience.

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Due to the recent boom in urbanisation, economy, and global population, the amount of waste generated worldwide has increased tremendously. The World Bank estimates that global waste generation is expected to increase 70% by 2050. Disposal of waste is already a major concern as it poses risks to the environment, human health, and economy.

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Bioconversion of food waste into sophorolipid-based biosurfactants is a promising emerging technology. It is important to evaluate the environmental impacts associated with the latest advancements in sophorolipid production as it matures to maximize sustainability on scale-up. This study takes a dynamic Life Cycle Assessment (dLCA) approach to address the inherent uncertainties and evaluate the environmental performances.

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Microbial biosurfactants are surface-active molecules that are naturally produced by a range of microorganisms. They have certain advantages over chemical surfactants, such as lower toxicity, higher biodegradability, anti-tumor, and anti-microbial properties. Sophorolipids (SLs) in particular are one of the most promising biosurfactants, as they hold the largest share of the biosurfactant market.

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Article Synopsis
  • Significant advancements have been made in the design of organic semi-conducting conjugated polymers that effectively transport charges and emit light, involving the use of electron-donating and electron-withdrawing units in their structure.
  • These conjugated materials are highly effective in sensing toxic substances, metal ions, and biomolecules due to their unique electronic properties, which allow for enhanced fluorescence intensity.
  • The review discusses various aspects of these polymers, including their fluorescence behavior, ability to detect multiple metal ions, solubility, stability, and how different functional groups can modify their optoelectronic properties.
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In spite of advances in tuberculosis (TB) chemotherapy, TB is still airborne deadly disorder as a major issue of health concern worldwide today. Extensive researches have been focused to develop novel drug delivery systems to shorten the lengthy therapy approaches, prevention of relapses, reducing dose-related toxicities and to rectify technologically related drawbacks of anti-tubercular drugs. Moreover, the rapid emergence of drug resistance, poor patient compliance due to negative therapeutic outcomes and intracellular survival of Mycobacterium highlighted to develop carrier with optimum effectiveness of the anti-tubercular drugs.

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Cellulose blended hyperbranched polyester (CHP) and hyperbranched cellulose polyester (HPC) were synthesized by melt condensation method using 2,2-bis (methylol) propionic acid and p-TSA. Obtained polymers were utilized for the preparation of various donepezil loaded thinfilm (CHPF, HPCF) and nanofibers (CHPN, HPCN) using solvent casting and electrospinning technique respectively. Formulated thinfilms and nanofibers were subjected to thermal analysis and microscopic evaluations.

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Chitosan micro sized ODF (CBF), chitosan nano sized ODF (CNF) and chitosan nanofiber (CNfib) were prepared to release the donepezil drug quickly for Alzheimer's disease. CNF and CNfib were prepared from ionic gelation technique and electro-spinning process which were further examined under in vitro and in vivo animal model studies. Good thermal stability of CNfib (450°C) when compared to CBF (325°C) and CNF (305°C).

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