Health and quality of life in adults with Noonan syndrome.

Objective: To obtain information on health and quality of life in adults with Noonan syndrome.

Study Design: From a cohort of 144 children with the diagnosis of Noonan syndrome whose height data had been published 23 years ago, 103 pediatric files providing adequate data were identified. Participants were sent questionnaires and asked to provide saliva for DNA analysis and to return for physical examination.