Introduction: Plasma concentrations of gut microbial metabolites are associated with cardiomyocyte viability and platelet reactivity. We hypothesized that increased concentrations of gut metabolites may predict major adverse cardiac and cerebrovascular events (MACCE) after acute myocardial infarction (AMI).
Aim: The primary objective of this study was to evaluate the association between elevated plasma concentrations of gut metabolites and MACCE after AMI.
Aortic valve interstitial cells (VICs) constitute a heterogeneous population involved in the maintenance of unique valvular architecture, ensuring proper hemodynamic function but also engaged in valve degeneration. Recently, cells similar to telocytes/interstitial Cajal-like cells described in various organs were found in heart valves. The aim of this study was to examine the density, distribution, and spatial organization of a VIC subset co-expressing CD34 and PDGFRα in normal aortic valves and to investigate if these cells are associated with the occurrence of early signs of valve calcific remodeling.
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July 2019
Celiac artery (trunk) is one of the three major arteries which arise from abdominal aorta. It's variations not seem to be very uncommon. A routine dissection of a male cadaver at Department of Anatomy Jagiellonian University revealed unusual branching pattern of the celiac trunk with numerous supernumerary hepatic arteries.
View Article and Find Full Text PDFThis paper reports on the properties of bilayers composed of dioctadecyldimethylammonium bromide (DODAB) and oleic acid (OA) at various molar ratios. The mole fraction of OA, X(OA), was varied in the range of 0-1 and the total lipid content was constant and equal to 10 mM. The DODAB/OA dispersions were extruded at a temperature higher than that of the gel-liquid transition of DODAB.
View Article and Find Full Text PDFIn this work the Langmuir monolayer technique was applied to study the interactions between phosphatidylglycerol (PG) and phosphatidylethanolamines (PEs). Since the technique of monomolecular layers is useful method of modeling of biomembranes and the investigated lipids are the major components of Gram-negative bacteria bilayers the results obtained were discussed in the context of the properties of bacterial membranes. To investigate the influence of the phosphatidylethanolamine acyl chain structure on its miscibility and interactions with dipalmitoylphosphatidylglycerol (DPPG) the chosen phosphatidylethanolamines differed both in the length (dipalmitoylphosphatidylethanolamine (DPPE), distearoylphosphatidylethanolamine (DSPE)), and saturation (dioleoylphosphatidylethanolamine (DOPE)) of the hydrocarbon chains.
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