Publications by authors named "Karolina Talandyte"
Epilepsy is caused when rhythmic neuronal network activity escapes normal control mechanisms, resulting in seizures. There is an extensive and growing body of evidence that the onset and maintenance of epilepsy involves alterations in the trafficking, synaptic surface expression and signalling of kainate and AMPA receptors (KARs and AMPARs). The KAR subunit GluK2 and AMPAR subunit GluA2 are key determinants of the properties of their respective assembled receptors.
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- SUMOylation is a process that modifies proteins after they are made, impacting their shape and how they interact with other proteins.
- Recent research shows that SUMOylation occurs not only in the nucleus but also affects proteins outside the nucleus, playing a key role in brain development and functioning.
- This review highlights new findings on SUMO target proteins at synapses and explores how these findings could affect our understanding of brain cell functions.