Publications by authors named "Karolina Podolska"
Article Synopsis
- The study analyzed 37 patients with Duchenne muscular dystrophy (DMD) aged 8-18, focusing on how neurological and cardiac factors affect their quality of life (QoL).
- Findings indicated that reduced upper limb movement correlates negatively with mobility and daily activities, with noticeable differences between ambulatory and non-ambulatory patients.
- Cardiac assessments linked mitral annular plane systolic excursion (MAPSE) to mobility, but no significant connections were found between MAPSE and anxiety/depression, highlighting the complex interplay of DMD's effects on QoL.
Aim: The present work focused on the Sonic hedgehog (SHH) gene that stimulates angiogenesis in the skin. It is postulated that endothelial progenitor cells (EPCs) are responsible for skin angiogenesis. The recruitment of endothelial progenitor cells was verified in the mouse skin transfected with the pSHH gene construct using the quantitative PCR method.
View Article and Find Full Text PDFGene therapy is recognized to be a novel method for the treatment of various disorders. Gene therapy strategies involve gene manipulation on broad biological processes responsible for the spreading of diseases. Cancer, monogenic diseases, vascular and infectious diseases are the main targets of gene therapy.
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