Electrophile-Dependent Reactivity of Lithiated -Benzylpyrene-1-Carboxamide.

In this paper, we describe the lithiation of -benzylpyrene-1-carboxamide with RLi-TMEDA. We found that the reaction outcome strongly depends on the electrophile used in the quenching step. The electrophile can be introduced at either the benzylic position or at the C-2 position in the pyrene nucleus.