Publications by authors named "Karolina Kopka"
Patients with unstable angina present clinical characteristics of atherosclerotic plaque vulnerability, contrary to chronic coronary syndrome patients. The process of athersclerotic plaque destabilization is also regulated by microRNA particles. In this study, the investigation on expression levels of microRNAs inhibiting the expression of proteins that protect from atherosclerotic plaque progression (miR-92a inhibiting KLF2, miR-10b inhibiting KLF4, miR-126 inhibiting MerTK, miR-98 inhibiting IL-10, miR-29b inhibiting TGFβ1) was undertaken.
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- Diabetes mellitus (DM) negatively impacts skin wound healing, and there are limited treatments available to help with this issue.
- This study explored the effects of N-acetylcysteine (NAC), an antioxidant, on wound healing using a mouse model with type II DM, comparing different concentrations of NAC in hydrogels against a placebo.
- The results showed that a 5% NAC concentration significantly improved wound healing speed and dermal proliferation, while higher concentrations did not enhance the healing process.