Publications by authors named "Karolina Frankova"
Polymer-free hydrogel made of lipid nanocapsules, as a local drug delivery platform.
Mater Sci Eng C Mater Biol Appl
July 2021
Article Synopsis
- - Nanoparticle-loaded hydrogels combine the benefits of hydrogel (like sustained drug release) and nanoparticles (offering targeting and reduced toxicity); traditional designs use a polymer matrix for gel formation.
- - The study introduces lipid nanocapsule (LNC)-based hydrogels that function without a polymer matrix by using a modified drug (CytC16) to link LNCs, resulting in a novel, gelled structure that retains useful viscoelastic properties.
- - These innovative hydrogels offer controlled drug release and reduce toxicity risks post-administration since they leave no lingering gel residue, highlighting their potential as effective drug delivery systems.