Publications by authors named "Karolina Buszka"
Despite the rising public awareness of the risk factors and the possible prevention of melanoma development, it remains challenging in terms of diagnosis and treatment. To improve the clinical situation of patients, it would be especially beneficial to develop prognostic methods for the effective and continuous assessment of the disease course. The solution could lie in the selection of effective biomarkers derived from the tumor microenvironment, increasing the effectiveness of melanoma prognoses and monitoring.
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- The treatment of non-small cell lung cancer (NSCLC) has improved with targeted therapy using tyrosine kinase inhibitors (TKIs), which helps patients with specific gene alterations achieve longer progression-free survival (PFS).
- Liquid biopsy techniques, like the analysis of circulating tumor cells (CTCs) and cell-free DNA (cfDNA), are becoming important for diagnosing and monitoring NSCLC patients, providing a less invasive alternative to traditional tissue biopsies.
- While current studies show promise for these methods, further large-scale prospective research is needed to validate their effectiveness in clinical settings before widespread use.
Article Synopsis
- Liquid biopsy refers to the analysis of circulating tumor cells and biomarkers like ctDNA, offering benefits such as easy blood sample collection and ongoing tracking of tumor growth.
- This technique also helps identify drug resistance mechanisms in various cancer treatments, although its effectiveness for melanoma patient management needs more research.
- The review compiles recent findings on CMCs and discusses the biology and detection methods of different liquid biopsy components, supporting the idea that careful biomarker selection can enhance precision medicine in cancer care.