Synthesis of new β(2,2)-amino acids with carbohydrate side chains: impact on the synthesis of peptides.

The study describes the synthesis of new geminally disubstituted C-linked carbo-β(2,2)-amino acids (β(2,2)-Caas) with different carbohydrate side chains, and their use in the synthesis of β(2,2)-peptides. The study infers that the side chain has an influence on the synthesis of peptides and their conformational behaviour.