Publications by authors named "Karmjot Singh Hundal"
Article Synopsis
- SLC4A11 mutations are linked to various corneal dystrophies and associated conditions like Harboyan syndrome.
- Research on mice missing the Slc4a11 gene shows they develop issues similar to congenital hereditary endothelial dystrophy, emphasizing the protein's role in corneal health.
- Five specific SLC4A11 mutations were analyzed in a cell line, revealing that, while there were no significant differences in protein levels at the cell surface, all mutations led to reduced acidification and H ion currents compared to the wild type, indicating altered transport properties rather than protein trafficking issues.
Regulation of uterine contractility is an important aspect of women's health. Phenylephrine, a selective agonist of the α-adrenoceptor and a potent smooth muscle constrictor, is widely used in women even during pregnancy to relieve cold-related symptoms, to treat postpartum haemorrhoid, and during routine eye exams. We performed isometric tension recordings to investigate the effect of phenylephrine on mouse uterine contractility.
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