Non-compliance with disease modifying therapies in patients with Multiple Sclerosis: A qualitative analysis.

Background: Factors associated with adherence to disease modifying therapies (DMT) in patients with Multiple Sclerosis (MS) have been reported before, but little has been studied on compliance to a physician's initial treatment recommendations. The objective of this study was to assess the factors associated with compliance to physician recommended treatment in treatment-naïve patients with MS.

Methods: We studied a cohort of patients with MS followed at an academic MS center in Toronto, Canada between January 2015 and May 2018.

Evaluation of ethnicity as a predictor of diagnostic phenotype and prognosis in neuromyelitis optica spectrum disorder in Toronto, Canada.

Background: Recent international studies suggest that ethnicity may predict relapse types and outcomes in NMOSD. Our aim was to evaluate ethnicity as a predictor of diagnostic phenotype and prognosis in a multi-ethnic NMOSD cohort from a single geographic region.

Methods: This was a multi-centre retrospective cohort study of NMOSD subjects in Toronto, Canada.