The species and quantitative composition of the bile microflora, peritoneal exudate, colonic cavity and mucosa was studied in 55 patients and in experiment on 17 mongrel dogs to estimate efficacy of application of colonosanation method in treatment of an acute peritonitis of biliary origin. It was established that in occurrence of peritonitis of biliary origin the essential role play disorders of intestinal microbic landscape and his colonizing resistance. Application of elaborated method of colonosanation had permitted to a considerable extent to eliminate these disorders and to improve result of treatment of the patients.
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