The use of maize haploidy inducers as a tool in agricultural plant biotechnology.

The discovery of the ability of some mutations to stimulate haploidy during hybridization made it possible to create one of the most promising and sought-after trends in the f ield of reproductive biology. Haploid inducers created on their basis are capable of increasing the frequency of haploidy up to 15 %. The improvement of the existing haploid inducer lines and the search for new genes that contribute to a high frequency of haploidy are underway.

[Dyssynergic defecation is one of the causes of chronic constipation].

Aim: To define the rate and type distribution of dyssynergic defecation (DD) in patients with primary chronic constipation (CC) and to evaluate the efficiency of biofeedback (BFB) therapy.

Subjects And Methods: One hundred and thirty-two 18-to-89-year-old patients treated in the Moscow Clinical Research and Practical Center for primary CC were examined using proctological examination, colonofibroscopy, anorectal manometry (ARM), and the balloon expulsion test.

Results: Different types of DD were identified in 44.

[Control of myocardial ischemia in patients with effort angina and polyvascular atherosclerotic involvement].

In patients with ischemic heart disease with various degree of severity of atherosclerotic involvement of peripheral arteries maintenance of target levels of arterial pressure and heart rate with the help of therapy which includes cardioselective -adrenoblocker as a preparation of choice with addition if necessary of a calcium antagonist and angiotensin converting enzyme inhibitor allows to successfully control myocardial ischemia and heart rate under conditions of everyday life.

Computational and experimental studies of size and shape related physical properties of hydroxyapatite nanoparticles.

In this work, the properties of hydroxyapatite (HAP) nanoparticles (NPs) have been studied both theoretically and experimentally focusing on computational analysis. HAP is widely used to fabricate implants, for drug delivery, etc. The physical properties of the nanosized HAP particles play an important role in the interaction with cells in the human body and are of great interest.

Electronic states spectroscopy of hydroxyapatite ceramics.

Photoluminescence, surface photovoltage spectroscopy and high-resolution characterization methods (Atomic Force Microscopy, Scanning Electron Microscopy, X-ray spectroscopy and DC conductivity) are applied to nanostructured Hydroxyapatite (HAp) bioceramics and allowed to study electron (hole) energy states spectra of the HAp and distinguish bulk and surface localized levels. The measured trap spectra show strong sensitivity to preliminary heat treatment of the ceramics. It is assumed that found deep electron (hole) charged states are responsible for high bioactivity of the HAp nanoceramics.

Relationship between osteogenic characteristics of bone marrow cells and calcium phosphate surface relief and solubility.

The capacity of mouse bone marrow cells to adhere to calcium phosphate surfaces and form tissue plates depending on the surface relief and solubility was studied in ectopic bone formation test. Calcium phosphate coating of titanium disks, made by the anodic spark (microarch) oxidation in 10% orthophosphoric acid with hydroxyl apatite particles, differed by the structure (thickness of coating, size of pores, and roughness) and solubility (level of in vitro oxidation of 1-week extracts of implants). Chemical (phasic and element) composition of the studied calcium phosphate coatings was virtually the same.

[Errors and complications of total endoprosthesis of the knee joint with the prostheses "Waldemar Link"].

The article presents results of an analysis of errors and complications for total endoprosthesing different pathological states of the knee joint with prostheses "Waldemar Link". The causes of early and late complications were found. The authors have developed original means for prevention and treatment of them.

Osteogenic potential of mesenchymal stem cells from bone marrow in situ: role of physicochemical properties of artificial surfaces.

Correlation analysis demonstrated the role of inorganic parameters of the surfaces of calcium phosphate materials in the regulation of osteogenic differentiation of mesenchymal precursors. The progenitor stromal cells were isolated from syngeneic bone marrow immobilized in vitro on calcium phosphate surfaces with different structure, phasic, and elemental composition. After 45 days of subcutaneous ectopic osteogenesis in BALB/c mice, the tissues grown on these matrixes were characterized histologically.

In vitro regulation of cell behavior by calcium phosphates synthesized by the mechanochemical method.

Biological activity of eight hydroxyapatite powders synthesized by the mechanochemical method was studied in vitro. Introduction of copper and zinc atoms into synthetic hydroxyapatite structure promotes cell adhesion. Hydroxyapatites obtained by the mechanochemical method are promising base for a new class of materials and coatings with regulated bioactivity for orthopedics and traumatology.

Adhesion of Staphylococcus aureus to implants with different physicochemical characteristics.

Adhesion of pathogenic Staphylococcus aureus (strain 209) to BT1-0 titanium disks (12 mm in diameter) with different coatings and noncoated was studied in vitro by photocolorimetry. Transparency of bacterial suspension in normal saline was evaluated after 2-h culturing with the implants at 37 degrees C. The decrease of S.

[Changes in regional hemostasis in the extremities of patients with cerebral circulatory disorders].

A new method of the prophylaxis and treatment of prethrombotic states (automatic pneumomassage) was employed in patients kept on bed rest.