Publications by authors named "Karlinde Spit"
: This study aims to describe a prospective clinical cohort of patients with silicone breast implants and suspected Breast Implant Illness (BII). : Women were included in a specialized silicone outpatient clinic at Amsterdam UMC, the Netherlands. Baseline characteristics were collected including medical history, implant details, and symptoms.
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- Silicone breast implants often face issues like ruptures and gel bleed, and while MRI is seen as the best imaging method, recent studies indicate that ultrasound might also be effective.
- This study involved 104 women who underwent both ultrasound and MRI on the same day, with radiologists evaluating the results for accuracy in detecting implant ruptures and silicone deposits in lymph nodes.
- Findings revealed that ultrasound was highly accurate (96%) for detecting ruptures and was better than MRI for finding silicone in lymph nodes, leading to a recommendation to start examinations with ultrasound before using MRI if needed.
Background: The etiology of capsular contracture (CC), the most common complication following breast augmentation, remains unclear. Chronic, fibrotic inflammation resulting in excessive fibrosis has been proposed as a potential mechanism.
Objectives: In this study, we aimed to investigate the relation between biomarkers that are associated with inflammation and fibrosis and the severity of CC.
Breast augmentation is a widely performed surgical procedure worldwide, predominantly using silicone gel-filled implants. Concerns have primarily revolved around ruptures and the potential health risks associated with leaked silicone from silicone gel-filled implants. Cases of silicone migration from the shell of saline breast implants remain scarce.
View Article and Find Full Text PDFObjective: An unknown portion of women with silicone breast implants (SBI) report development of systemic symptoms, recently named as 'breast implant illness (BII)'. We aim to describe the symptoms and characteristics of women with SBI reporting these systemic symptoms and compare the clinical course of women who chose to keep their implants, to women who had their implants removed.
Design: Observational cohort study.
Objectives: Increased renal sinus fat (RSF) is associated with hypertension and chronic kidney disease, but underlying mechanisms are incompletely understood. We evaluated relations between RSF and gold-standard measures of renal hemodynamics in type 2 diabetes (T2D) patients.
Methods: Fifty-one T2D patients [age 63 ± 7 years; BMI 31 (28-34) kg/m; GFR 83 ± 16 mL/min/1.
Aspirin is traditionally taken once daily in the morning and considered to be effective throughout the 24h interval. Cardiovascular events occur most frequently in the early morning, suggesting that these hours are critical in terms of adequate platelet inhibition. This study therefore assed platelet function in the early morning-8.
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