Publications by authors named "Karla P de O Luna"
Article Synopsis
- Bothrops leucurus is a major cause of snakebites in Northeast Brazil, but its venom is not included in current antivenom production, prompting the exploration of alternative treatments.
- Chlorogenic acid and rosmarinic acid were studied for their ability to inhibit B. leucurus venom's enzymatic activity and harmful effects, showing significant effectiveness in reducing edema, hemorrhage, and myotoxicity in both in vitro and in vivo tests.
- The compounds demonstrated interactions with venom components and proved to be more effective than existing antivenoms, suggesting their potential as complementary treatments in snakebite management.
The Caatinga lancehead, Bothrops erythromelas, is a medically relevant species, responsible for most of the snakebite accidents in most parts of its distribution range in northeastern Brazil. The spectrum and geographic variability of its venom toxins were investigated applying a venomics approach to venom pools from five geographic areas within the Caatinga ecoregion. Despite its wide habitat, populations of B.
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