Publications by authors named "Karla Lorene DE Franca Leite"
Objectives: This study aimed to evaluate the physical-mechanical, chemical, and biological properties of graphene-reinforced glass ionomer cements (GICs).
Materials And Methods: Different proportions of graphene powder were incorporated into 2 high-viscosity self-curing GIC, Ketac Molar (G) and Fuji IX (G), in 4 different concentrations: 0.5%, 1%, 2%, and 5%.
ARE PIT AND FISSURE SEALANTS EFFECTIVE IN PREVENTING AND ARRESTING OCCLUSAL CARIES IN PRIMARY AND PERMANENT TEETH? AN OVERVIEW OF SYSTEMATIC REVIEWS.
J Evid Based Dent Pract
September 2024
Objectives: To compile the evidence from systematic reviews (SRs) about the use of sealants for preventing and arresting pit and fissure occlusal caries in primary and permanent teeth.
Materials And Methods: A search was performed in six databases and gray literature up to May 2023. Systematic reviews (SRs) that included randomized trials (RCTs) and nonrandomized clinical trials (n-RCTs) aiming to answer the PICO-based focused question "are pit and fissure sealants (I) more effective than other interventions, control or no treatment (C) in preventing and arresting occlusal caries (O) in primary and permanent teeth (P)?", were included.
Influence of the use of bisphosphonates on the development of postextraction sequelae: Scoping review with mapping evidence of in vivo studies.
J Dent
September 2024
Article Synopsis
- The review aimed to analyze the current understanding of medication-related osteonecrosis of the jaw (MRONJ) linked to tooth extractions in patients undergoing bisphosphonate therapy, addressing knowledge gaps for future research.
- It evaluated a total of 176 studies, with 41.4% focusing on animal models and 58.5% on human subjects, revealing that zoledronic acid was the most studied bisphosphonate, especially with intravenous use.
- Key findings indicated that the mandible was the primary site of complications, with bone necrosis identified as the most common consequence in both animal (53.4%) and human (22.1%) studies, emphasizing the need for vigilance in patients with a history of
In-vitro effect of a single application of CPP-ACP pastes and different fluoridated solutions on the prevention of dental caries around orthodontic brackets.
Dental Press J Orthod
January 2024
Objective: To assess the in-vitro effect of single applications of CPP-ACP pastes and different fluoridated solutions on the prevention of dental caries around orthodontic brackets.
Material And Methods: Tooth/bracket sets (n=65) were immersed in artificial saliva (1h at 37ºC) and randomly subjected to single applications (100µL; 1min) of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP emulsion), CPP-ACP with fluoride (CPP-ACPF emulsion), solutions of titanium tetrafluoride (TiF4) or sodium fluoride (NaF), or no treatment (CG). Multispecies biofilm (5 x 105 CFU/mL) was formed in the presence of 2% sucrose.
To assess the in vitro and in situ effect of experimental combined fluoride and calcium nanocomposite solutions on dental caries prevention. Nanocompound mesoporous silica (MS) with calcium (Ca) and sodium fluoride (NaF) - (MSCaNaF); MS with NaF (MSNaF), NaF solution (positive control), and deionized water (negative control - CG) were studied. The specimens (n=130) were submitted in vitro to a multispecies biofilm in the presence of 2% sucrose.
View Article and Find Full Text PDFIntroduction: Titanium tetrafluoride (TiF4) is a fluoride compound that, when is applied over enamel, promotes a protection against demineralization through a titanium dioxide (TiO2) acid-resistant coat.
Objectives: This study sought to verify the hypothesis that a single application of 4% TiF4 increases the resistance of enamel to dental demineralization in orthodontic patients.
Materials And Methods: This controlled clinical trial followed CONSORT guidelines and investigated the prevention of enamel demineralization, fluoride retention, and the presence of a Ti layer after TiF4 application on banded teeth exposed to clinical cariogenic biofilm.
Article Synopsis
- - The study aimed to evaluate how effective titanium tetrafluoride (TiF) is compared to other fluoride treatments, placebo solutions, or negative controls in preventing or treating dental caries and tooth erosion.
- - A systematic review following PRISMA guidelines analyzed 28 studies, including both human and animal research, while assessing the risk of bias in each study, indicating that most studies had significant flaws.
- - While some evidence suggests that TiF4 may positively affect caries prevention and treatment, the varied quality and methodology of the studies prevent definitive conclusions, highlighting the need for more rigorous research.
This study aimed to evaluate the in vitro effect of a single application of experimental nanocomposite solutions on the prevention of dental caries around orthodontic brackets. The specimens were exposed to mesoporous silica (MS) nanocomposites containing fluoride by association with titanium tetrafluoride (TiF4) or sodium fluoride (NaF). Nanocomposites also could contain calcium and groups were described as MSCaTiF4, MSTiF4, MSCaNaF, MSNaF, and controls (TiF4, and NaF).
View Article and Find Full Text PDFBackground: To evaluate the antifungal activity of the red propolis hydroalcoholic extract (RPHE) against biofilms.
Material And Methods: The minimum inhibitory and fungicidal concentrations (MIC and MFC) of the RPHE were determined by the microdilution technique. biofilms were formed on the surface of resin specimens preconditioned with artificial saliva (1h).
Objective: We sought to revise, qualify and summarize the body of evidence based on current information on the known associations and risk factors for traumatic dental injury (TDI) occurrence with an overview of systematic reviews.
Methods: Electronic searches were performed with no language nor date restrictions.According to the PECO strategy, systematic reviews that investigated participants (P) with (E) and without (O) the presentation of factors relating to TDI and these factors' association with TDI episodes (O) as primary or secondary outcomes were included.
Objective: The aim of this study was to evaluate the morphological and chemical effect of in-office and at-home desensitising agents containing sodium fluoride (NaF) on eroded root dentine in vitro.
Methods: Fifty bovine dentine samples were pre-eroded and randomised into five groups (n = 10): G1 (Control) - milli-Q water; G2 - fluoride varnish containing NaF 22,500 ppm; G3 - desensitising cream containing NaF 9,000 ppm associated with 20% nanohydroxyapatite; G4 - toothpaste with NaF 5,000 ppm associated to tricalcium phosphate; G5 - toothpaste containing NaF 900 ppm and casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF). The specimens were submitted to erosive challenge for three days.
Introduction And Aims: Traumatic dental injuries (TDI), alcohol and illicit drugs consumption are highly-prevalent public health concerns. The aim of this study was to evaluate the association between alcohol and/or illicit drugs consumption and the presence of TDI.
Design And Methods: This review was performed in accordance with MOOSE and PRISMA guidelines.
Efficacy of red propolis hydro-alcoholic extract in controlling Streptococcus mutans biofilm build-up and dental enamel demineralization.
Arch Oral Biol
September 2018
Objective: The efficacy of a red propolis hydro-alcoholic extract (RP) in controlling Streptococcus mutans biofilm colonization was evaluated. The effect of RP on dental demineralization was also investigated.
Methods: Chemical composition was determined by High Performance Liquid Chromatography (HPLC).