Publications by authors named "Karla Gonzalez-Alvarado"
Extracellular vesicles (EVs) are defined as subcellular structures limited by a bilayer lipid membrane that function as important intercellular communication by transporting active biomolecules, such as proteins, amino acids, metabolites, and nucleic acids, including long non-coding RNAs (lncRNAs). These cargos can effectively be delivered to target cells and induce a highly variable response. LncRNAs are functional RNAs composed of at least 200 nucleotides that do not code for proteins.
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- Cancer causes over 10 million deaths annually, and issues like metastasis and drug resistance significantly lower survival rates, presenting challenges for effective treatment.
- Long non-coding RNAs, particularly linc-ROR, play a key role in cancer by interacting with micro RNAs and are increasingly recognized for their involvement in cancer development and progression.
- This review aims to provide updated insights into linc-ROR's role in cancer, emphasizing its potential to enhance diagnostic tools and targeted therapies in precision oncology.