Salvadoran Celastraceae Species as a Source of Antikinetoplastid Quinonemethide Triterpenoids.

Chagas disease and leishmaniasis are among the most widespread neglected tropical diseases, and their current therapies have limited efficacy and several toxic side effects. The present study reports the chemical and antikinetoplastid profiles of extracts from five Salvadoran Celastraceae species against the epimastigotes stage and and promastigote forms. The phytochemical profile evinced the presence of flavonoids, tannins, sterols, and triterpenes as the main components in all plant species, whereas quinonemethide triterpenoids (QMTs) were restricted to the root bark of the studied species.

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Objective: To analyze the prevalence of domestic violence in adult women during confinement derived from the Co-vid-19 pandemic and individual, familiar and communitarian associated factors.

Materials And Methods: A second-ary analysis was carried out the 2020 National Health and Nutrition Survey on Covid-19, with national representation. A logistic regression model adjusted for the variables of interest was performed.

Fat mass obesity-associated () (rs9939609) and melanocortin 4 receptor () (rs17782313) SNP are positively associated with obesity and blood pressure in Mexican school-aged children.

Childhood overweight and obesity are worldwide public health problems and risk factors for chronic diseases. The presence of SNP in several genes has been associated with the presence of obesity. A total of 580 children (8-13 years old) from Queretaro, Mexico, participated in this cross-sectional study, which evaluated the associations of rs9939609 (fat mass obesity-associated ()), rs17782313 (melanocortin 4 receptor ()) and rs6548238 (transmembrane protein 18 ()) SNP with obesity and metabolic risk factors.

[Mental health policies in Santa Catarina in the 1970s: the vanguard of Brazilian psychiatry?].

Highlighting the social and economic context, the article examines the changes in psychiatric care in the state of Santa Catarina from 1971 through 1975. Guided by experts from the Pan American Health Organization, the state government devised a mental health policy that was based on U.S.