Subproteome of venom and preliminary studies on LmrSP-4, a novel snake venom serine proteinase.

Background: is one of the venomous snakes of medical importance in Brazil whose envenoming is characterized by local and systemic effects which may produce even shock and death. Its venom is mainly comprised of serine and metalloproteinases, phospholipases A and bradykinin-potentiating peptides. Based on a previously reported fractionation of venom (LmrV), we decided to perform a subproteome analysis of its major fraction and investigated a novel component present in this venom.