Publications by authors named "Karla Carolina Paiva Bocate"
Rhamnogalacturonan, a chemically-defined polysaccharide, improves intestinal barrier function in DSS-induced colitis in mice and human Caco-2 cells.
Daniele Maria-Ferreira Adamara Machado Nascimento Thales Ricardo Cipriani Arquimedes Paixão Santana-Filho Paulo da Silva Watanabe Karla Carolina Paiva Bocate
Sci Rep
August 2018
Article Synopsis
- Natural polysaccharides like rhamnogalacturonan (RGal) from Acmella oleracea have shown beneficial effects in treating intestinal inflammation.
- In mouse models of colitis, RGal reduced weight loss and tissue damage while improving colon health and promoting cell growth.
- In lab tests with human colorectal cancer cells, RGal enhanced barrier function and expedited wound healing, suggesting its potential as a treatment for ulcerative colitis.