[Letrozole vs. tamoxifen as neoadjuvant therapy for postmenopausal patients with hormone-dependent locally-advanced breast cancer].

Background: Previous studies demonstrated that Letrozole (aromatase inhibitor) and tamoxifen (selective modulator of estrogen receptors) are effective in the treatment of postmenopausal women with locally advanced tumors, stage III and hormone dependent.

Objective: To present display the complete clinical answer incidence and the complete pathological answer with the use of induction hormonotherapy.

Methods: Put-analysis in 40 patients with breast cancer, to chanalicular infiltrated, eligible were treated in a prospective study, to double blind person, using per os: letrozol, 2.

[A clinical guideline for diagnosis and treating of diabetes during pregnancy].

Background: Metabolic disturbance commonly occurs during pregnancy and perinatal outcome harms, with increased maternal-fetal morbidity. The prevalence of diabetes during pregnancy in Mexico is 7%.

Objective: To develop a guideline available to the staff of the first, second and third level of care, that includes recommendations based on the best available evidence.