Influence of Individual Heart Rate on Nonlinear Brain-Heart Interactions Estimated by Convergent Cross Mapping in Schizophrenic Patients and Healthy Controls.

Quantification of directed (nonlinear) brain-heart interactions has turned to be an emerging topic of research and is important for the better understanding of central autonomic processing during specific diseases such as schizophrenia. Convergent Cross Mapping (CCM) was able to provide directed, frequency-selective and topographic views on existent interaction pattern of those patients. Investigations of the influence of individual heart rate (HR) on CCM estimations may further contribute to this topic.

Nonlinear Interaction Analysis of Cardiovascular-Respiratory Data by Means of Convergent Cross Mapping.

Appropriate analyses of directed complex interactions within the cardiovascular-respiratory system are of growing interest for a better understanding of physiological regulatory mechanisms in healthy subjects and diseased persons. There are various concepts to analyze such interactions. Convergent Cross Mapping (CCM) provides the possibility to define directed interactions in terms of nonlinear stability.