Identification of differential gene expression patterns in human arteries from patients with chronic kidney disease.

Uremia accelerates atherosclerosis, but little is known about affected pathways in human vasculature. This study aimed to identify differentially expressed arterial transcripts in patients with chronic kidney disease (CKD). Global mRNA expression was estimated by microarray hybridization in iliac arteries ( n = 14) from renal transplant recipients and compared with renal arteries from healthy living kidney donors ( n = 19) in study 1.

Avoiding steroids in pediatric renal transplantation: long-term experience from a single centre.

We report our experience in pediatric renal transplantation avoiding steroids whenever possible. Immunosuppression consisted of an initial induction with antithymocyte globulin followed by maintenance therapy with a calcineurin inhibitor and MMF. Steroids were only given to selected patients because of the primary disease, recurrence, rejection, or PTLD.

[Endovascular treatment of abdominal aortic aneurysms].

Introduction: The endovascular method of treating abdominal aortic aneurysms was introduced as an alternative to conventional surgical repair in the hope of reducing the operative mortality and morbidity.

Material And Methods: Thirty patients were selected for endovascular aneurysm repair on the basis of anatomical criteria. The result of the treatment was evaluated by angiography on completion of surgery and by contrast-enhanced CT scans at 1, 3, 6, and 12 months, and annually thereafter.