Evaluate the accuracy of a 23-gene expression signature in differentiating benign nevi from melanoma by comparing test results with clinical outcomes. Seven dermatopathologists blinded to gene expression test results and clinical outcomes examined 181 lesions to identify diagnostically uncertain cases. Participants independently recorded diagnoses and responses to questions quantifying diagnostic certainty.
View Article and Find Full Text PDFBackground: Microvenular hemangioma is an uncommon benign vascular tumor that can potentially be mistaken for malignancy.
Methods: We reviewed the histopathologic and clinical features of 13 microvenular hemangiomas, which represents the largest series reported to date.
Results: The patients [female (F) = 8 and male (M) = 5] had a mean age of 39 years (range: 16 months-69 years).
Ganglioglioma and dysembryoplastic neuroepithelial tumor are both low-grade glioneuronal neoplasms that most commonly occur in association with chronic epilepsy. Rare cases of tumors with composite features of ganglioglioma and dysembryoplastic neuroepithelial tumor have been reported. We retrospectively reviewed the clinicopathologic features of 8 composite tumors (7 were female; median age, 20 years).
View Article and Find Full Text PDF