Publications by authors named "Karl M Napekoski"

Article Synopsis
  • - Cellulite is a common condition mainly affecting women, and CCH-aaes injections help improve its appearance by disrupting collagen structures, although bruising at the injection site is a common side effect.
  • - An animal study was conducted on female Yorkshire pigs to investigate the tissue changes after CCH-aaes injections, with pigs receiving either the treatment or a placebo at various time points.
  • - Results showed that CCH-aaes led to the breakdown of collagen in the subcutaneous layer soon after injection, with signs of inflammation early on, followed by new collagen formation and tissue remodeling observed by Day 21.
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Evaluate the accuracy of a 23-gene expression signature in differentiating benign nevi from melanoma by comparing test results with clinical outcomes. Seven dermatopathologists blinded to gene expression test results and clinical outcomes examined 181 lesions to identify diagnostically uncertain cases. Participants independently recorded diagnoses and responses to questions quantifying diagnostic certainty.

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Background: Microvenular hemangioma is an uncommon benign vascular tumor that can potentially be mistaken for malignancy.

Methods: We reviewed the histopathologic and clinical features of 13 microvenular hemangiomas, which represents the largest series reported to date.

Results: The patients [female (F) = 8 and male (M) = 5] had a mean age of 39 years (range: 16 months-69 years).

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Ganglioglioma and dysembryoplastic neuroepithelial tumor are both low-grade glioneuronal neoplasms that most commonly occur in association with chronic epilepsy. Rare cases of tumors with composite features of ganglioglioma and dysembryoplastic neuroepithelial tumor have been reported. We retrospectively reviewed the clinicopathologic features of 8 composite tumors (7 were female; median age, 20 years).

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