Publications by authors named "Karl Johannes Lackner"
Article Synopsis
- This study aimed to explore how changes in systemic medication relate to intraocular pressure (IOP) in a large population in Germany.
- Researchers analyzed data from the Gutenberg Health Study, measuring IOP and recording medication changes over a five-year period in thousands of participants.
- Results showed that starting selective beta-blockers reduced IOP, while stopping them increased it; other medications' effects on IOP appeared linked to accompanying drugs or blood pressure changes.
Bi-Gaussian analysis reveals distinct education-related alterations in spherical equivalent and axial length-results from the Gutenberg Health Study.
Graefes Arch Clin Exp Ophthalmol
June 2024
Purpose: The aim of this study is to investigate the distribution of spherical equivalent and axial length in the general population and to analyze the influence of education on spherical equivalent with a focus on ocular biometric parameters.
Methods: The Gutenberg Health Study is a population-based cohort study in Mainz, Germany. Participants underwent comprehensive ophthalmologic examinations as part of the 5-year follow-up examination in 2012-2017 including genotyping.
Much higher prevalence of keratoconus than announced results of the Gutenberg Health Study (GHS).
Graefes Arch Clin Exp Ophthalmol
November 2023
Unlabelled: Keratoconus appears to be a rare corneal disease with a prevalence previously estimated at 1:2000. The aim of our study was to investigate the prevalence of keratoconus in a large German cohort and to evaluate possible associated factors.
Method: In the population-based, prospective, monocentric cohort study, Gutenberg Health Study, 12,423 subjects aged 40-80 years were examined at the 5-year follow-up.