Sesquiterpene Lactones and Flavonoid from the Leaves of Basin Big Sagebrush ( subsp. ): Isolation, Characterization and Biological Activities.

This research is an exploratory study on the sesquiterpenes and flavonoid present in the leaves of subsp. . The leaf foliage was extracted with 100% chloroform.

Extraction, Isolation and Characterization of Bioactive Compounds from and Their Biological Significance: A Review.

Diverse medicinal plants such as those from the genus have been employed globally for centuries by individuals belonging to different cultures. Universally, species have been used to remedy various maladies that range from simple fevers to malaria. A survey conducted by the World Health Organization (WHO) demonstrated that 80% of the global population is highly reliant on herbal medicine for their primary healthcare.

Activity-dependent fluorescent labeling of bacterial cells expressing the TOL pathway.

3-Ethynylbenzoate (3EB) functions as a novel, activity-dependent, fluorogenic, and chromogenic probe for bacterial strains expressing the TOL pathway, which degrade toluene via conversion to benzoate, followed by meta ring fission of the intermediate catechol. This direct physiological analysis allows the fluorescent labeling of cells whose toluene-degrading enzymes have been induced by an aromatic substrate.

Determining the solution state orientation of a Ti enolate via stable isotope labeling, NMR spectroscopy, and modeling studies.

Our group has used Ti-promoted aldol additions with an oxazolidineselone as the chiral auxiliary with much success. In these reactions, the Se atom in the auxiliary both promotes stereospecific addition as well as reports on, through the use of 77Se NMR spectroscopy, the ratio of diastereomers produced and the geometry of intermediates as the reaction proceeds. Through stable isotope labeling and NMR spectroscopy, we are able to experimentally observe a Ti enolate in solution and gain insight into its structure and reactivity.