Publications by authors named "Karl D Sienerth"
Article Synopsis
- Endocrine disruptors like 17β-estradiol (E2) and estriol (E3) are common environmental pollutants linked to health risks, with their interactions with dissolved organic matter (DOM) affecting their concentration and impact.
- Researchers investigated how humic acid (HA), a component of DOM, binds to E2 and E3 using nuclear magnetic resonance (NMR) spectroscopy, discovering that binding primarily occurs at the aromatic ring even at low HA concentrations.
- Their findings were supported by additional assays, enhancing understanding of estrogen-HA interactions and showcasing the effectiveness of combining biochemical and analytical methods to study these binding processes.
We report on the synthesis of a platinum(IV) compound containing a di-2-pyridyl ketone (dpk) ligand that is stable both in its anhydrous form [Pt(dpk)Cl(4)] (1) and in its hydrated form [Pt(dpk-O-OH)Cl(3)].H-phenCl (2). The crystal structure of the hydrated form shows that one of the hydroxide groups from the resulting gem-diol has undergone a cyclometalation/condensation reaction resulting in an oxygen atom directly coordinated to the Pt(IV) center and the formation of H-phenCl.
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