Publications by authors named "Karl Christian Thies"

Article Synopsis
  • Exsanguination is a major cause of preventable death in severe trauma, making immediate hemorrhage control and blood product transfusion essential, but Germany has lagged in prehospital blood product transfusion (PHBT) adoption due to its fragmented emergency medical service system.
  • This review analyzed 333 relevant studies to assess the historical context, international practices, and the current state of PHBT research, which faces challenges in trial design and recruitment.
  • Despite inconclusive survival benefits from recent trials, there is evidence suggesting potential improvements in patient outcomes, with thousands of trauma patients in Germany possibly benefiting from PHBT each year.*
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Background: Currently, the data regarding the impact of prehospital postcardiac arrest anesthesia on target hemodynamic and ventilatory parameters of early postresuscitation care and recommendations on its implementation are rare. The present study examines the incidence and impact of prehospital postcardiac arrest anesthesia on hemodynamic and ventilatory target parameters of postresuscitation care.

Methods: In this multicentre observational study between 2019 and 2021 unconscious adult patients after out-of-hospital-cardiac arrest with the presence of a return-of-spontaneous circulation until hospital admission were included.

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Article Synopsis
  • - This study evaluates how well the SOFA and SAPS-II scores predict mortality following cardiac arrests in ICU patients, analyzing data from a German university hospital's ICU over three years.
  • - Findings show that while 29.8% of patients died during the ICU cardiac arrest, neither SOFA nor SAPS-II effectively predicted immediate mortality in these instances (P>0.05).
  • - However, SAPS-II was better at predicting hospital and one-year mortality, suggesting a cutoff value of 43.5 for hospital mortality with good specificity and sensitivity, and 40.5 for one-year mortality, indicating its potential usefulness in clinical settings.
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Background: The aim of this study was to examine the impact of COVID-19 on the response rate of community-first-responders (CFR) and other out-of-hospital-cardiac-arrest (OHCA) outcomes using the smartphone-first-responder-system (SFRS) "Mobile Retter."

Methods: All adult non-traumatic OHCA in the district of Gütersloh between 01.01.

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The European Trauma Course (ETC) exemplifies an innovative approach to multispecialty trauma education. This initiative was started as a collaborative effort among the European Society for Emergency Medicine, the European Society for Trauma and Emergency Surgery, and the European Society of Anaesthesiology under the auspices of the European Resuscitation Council. With the robust support of these societies, the project has evolved into the independent European Trauma Course Organisation.

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Article Synopsis
  • An investigation was conducted to assess the impact of midazolam used for post-arrest sedation on achieving essential post-resuscitation care targets and the risk of hemodynamic complications in patients who experienced out-of-hospital cardiac arrest (OHCA).
  • The study reviewed emergency rescue missions from 2019-2021 and found that among patients with return of spontaneous circulation (ROSC), those receiving midazolam were more likely to meet recommended targets for blood pressure, oxygen levels, and carbon dioxide levels compared to those who did not receive sedation.
  • The results suggest that using midazolam during the pre-hospital phase improves the chances of meeting critical oxygenation and ventilation goals in post-arrest patients, indicating its potential benefit in
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Background: This experimental study was performed to evaluate the role of blended learning for technical skill teaching on the European Trauma Course (ETC). While online modules are extensively used for theoretical teaching, their role in skills training remains less well explored. The ETC currently relies on the established 4-step technique for teaching technical skills.

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Article Synopsis
  • In-hospital cardiac arrest scenarios were studied to assess the quality of chest compressions in different provider positions while resuscitating patients in hospital beds.
  • The research found that chest compressions performed from a of kneeling beside or astride the patient were more effective than standing, but less so than traditional floor-based compressions.
  • Kneeling positions yielded better compression quality and were subjectively rated as less fatiguing, suggesting they are preferable for emergency responders during in-bed resuscitation efforts.
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This study primarily aims to determine the frequency of life-threatening conditions among pediatric patients served by the DRF, a German helicopter emergency service (HEMS) provider. It also seeks to explore the necessity of invasive procedures in this population, discussing the implications for HEMS crew training and service configuration based on current literature. We analyzed the mission registry from 31 DRF helicopter bases in Germany, focusing on 7954 children aged 10 or younger over a 5-year period (2014-2018).

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Background: Although airway management for paramedics has moved away from endotracheal intubation towards extraglottic airway devices in recent years, in the context of COVID-19, endotracheal intubation has seen a revival. Endotracheal intubation has been recommended again under the assumption that it provides better protection against aerosol liberation and infection risk for care providers than extraglottic airway devices accepting an increase in no-flow time and possibly worsen patient outcomes.

Methods: In this manikin study paramedics performed advanced cardiac life support with non-shockable (Non-VF) and shockable rhythms (VF) in four settings: ERC guidelines 2021 (control), COVID-19-guidelines using videolaryngoscopic intubation (COVID-19-intubation), laryngeal mask (COVID-19-Laryngeal-Mask) or a modified laryngeal mask modified with a shower cap (COVID-19-showercap) to reduce aerosol liberation simulated by a fog machine.

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Background: The present study evaluated the implementation of the European Resuscitation Council Corona-Virus-Disease 2019 (COVID-19) resuscitation guidelines in Germany 1 year after publication.

Aim Of The Work: To evaluate the practical implementation of the COVID-19 resuscitation guidelines in Germany one year after their publication.

Material And Methods: In an online survey between April and May 2021 participants were asked about awareness of COVID-19 resuscitation guidelines, corresponding training, the resuscitation algorithm used and COVID-19 infections of emergency medicine personnel associated with COVID-19 resuscitation.

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Background: Out-of-hospital cardiac arrest is one of the most frequent causes of death in Europe. Emergency medical services often struggle to reach the patient in time, particularly in rural areas. To improve outcome, early defibrillation is required which significantly increases neurologically intact survival.

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Article Synopsis
  • Poor access to automatic external defibrillators (AEDs) and limited public knowledge on using them have led to inadequate defibrillation coverage in Germany.
  • This article explores the potential of using drones to deliver AEDs during out-of-hospital cardiac arrests, finding that drone deployment is feasible, safe, and may shorten response times.
  • While initial studies support AED drone use as beneficial in both rural and urban areas, adjustments in regulations and emergency service frameworks are necessary for effective integration.
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Background: Cardiac arrest in intensive care is a rarely studied type of in-hospital cardiac arrest.

Objective: This study examines the incidence, characteristics, risk factors for mortality as well as long-term prognosis following cardiac arrest in intensive care.

Design: Retrospective cohort study.

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Background: Dispatching first responders (FR) to out-of-hospital cardiac arrest in addition to the emergency medical service has shown to increase survival. The promising development of FR systems over the past years has been challenged by the outbreak of COVID-19. Whilst increased numbers and worse outcomes of cardiac arrests during the pandemic suggest a need for expansion of FR schemes, appropriate risk management is required to protect first responders and patients from contracting COVID-19.

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Background: Long patient transport times to trauma centers are a well-known problem in sparsely populated regions with a low hospital density. Transfusion of red blood cell concentrates (RBC) and plasma improves outcome of trauma patients with severe bleeding. Helicopter emergency services (HEMS) are frequently employed to provide early advanced medical care and to reduce time to hospital admission.

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Background: Community first responders (CFR) improve survival in out-of-hospital cardiac arrest (OHCA) but are often hampered by limited availability of public access defibrillation. Unmanned aerial systems (UAS) delivering automated external defibrillators (AED) directly to an OHCA site could help overcome this. We evaluated the feasibility of integrating UAS into the chain of survival in rural Northeast Germany.

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Background: Coronavirus disease 2019 (COVID-19) has brought about unprecedented challenges to medical schools. Physical distancing as the most effective means of infection prevention renders traditional classroom teaching nearly impossible and new teaching methods are required to contain the infection risk whilst ensuring high-level education.

Objective: In order to minimize the need for classroom teaching we have created an interactive multimedia eLearning environment using the open-source learning management system "Moodle".

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These guidelines of the European Resuscitation Council (ERC) Cardiac Arrest under Special Circumstances are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations. This section provides guidelines on the modifications required for basic and advanced life support for the prevention and treatment of cardiac arrest under special circumstances; in particular, specific causes (hypoxia, trauma, anaphylaxis, sepsis, hypo-/hyperkalaemia and other electrolyte disorders, hypothermia, avalanche, hyperthermia and malignant hyperthermia, pulmonary embolism, coronary thrombosis, cardiac tamponade, tension pneumothorax, toxic agents), specific settings (operating room, cardiac surgery, cardiac catheterization laboratory, dialysis unit, dental clinics, transportation [in-flight, cruise ships], sport, drowning, mass casualty incidents), and specific patient groups (asthma and chronic obstructive pulmonary disease, neurological disease, morbid obesity, pregnancy).

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